MSGene

MSGene - Polymorphism Details

Study:

Fernandez-Arquero, 1999

Gene:

TNF (DADB-70P7.1; DIF; TNF-alpha; TNFA; TNFSF2)

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Protein:

tumor necrosis factor (TNF superfamily, member 2) (APC1 protein; TNF superfamily, member 2; TNF, macrophage-derived; TNF, monocyte-derived; cachectin; tumor necrosis factor alpha)

Chromosome:

6 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 23 November 2011

Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs1800629 (-308G/A)	Spain	MS CTR	0.12 0.13	0.88 0.87	3 (0.013) 4 (0.012)	53 (0.223) 75 (0.231)	182 (0.765) 245 (0.756)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs361525 (-238A/G)	Spain	MS CTR	0.10 0.08	0.90 0.92	0 (0.000) 4 (0.012)	46 (0.193) 47 (0.145)	192 (0.807) 273 (0.843)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs1800750 (-376G/A)	Spain	MS CTR	0.08 0.05	0.92 0.95	0 (0.000) 2 (0.006)	40 (0.168) 27 (0.083)	198 (0.832) 295 (0.910)

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