MSGene

MSGene - Polymorphism Details

Study:

Mazzola, 2007

Gene:

PTGS2 (COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2)

Protein:

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (cyclooxygenase 2b; prostaglandin G/H synthase and cyclooxygenase; prostaglandin-endoperoxide synthase 2)

Chromosome:

1 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 28 October 2009

Total number of polymorphisms investigated by this study: 2

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	G-Allele	C/C (frequency)	C/G (frequency)	G/G (frequency)
Caucasian
rs20417 (-765 G/C)	Italy	MS CTR	0.24 0.23	0.76 0.77	8 (0.050) 7 (0.033)	61 (0.384) 85 (0.395)	90 (0.566) 123 (0.572)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	C-Allele	G/G (frequency)	G/C (frequency)	C/C (frequency)
Caucasian
rs20424 (-62C/G)	Italy	MS CTR	0.01 0.03	0.99 0.98	0 (0.000) 0 (0.000)	2 (0.020) 5 (0.050)	98 (0.980) 95 (0.950)

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