MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs12044852

Polymorphism:

rs12044852

Gene:

CD58 (RP5-1086K13.2; FLJ23181; FLJ43722; LFA-3; LFA3)

Protein:

CD58 molecule (CD58 antigen, (lymphocyte function-associated antigen 3); surface glycoprotein LFA-3)

Chromosome:

1 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011 ;

***Note that content for MSGene is still being curated and that most currently displayed pages (including this page) contain preliminary summaries and are still incomplete.***

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		A-Allele (frequency)	C-Allele (frequency)	A/A (frequency)	A/C (frequency)	C/C (frequency)
Caucasian	5	MS CTR	0.09 0.12	0.91 0.88	30 (0.008) 56 (0.014)	575 (0.160) 805 (0.203)	2995 (0.832) 3099 (0.783)
Total	5	MS CTR	0.09 0.12	0.91 0.88	30 (0.008) 56 (0.014)	575 (0.160) 805 (0.203)	2995 (0.832) 3099 (0.783)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs12044852

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

CD58_unknownSNPs
rs1016140
rs10802189
rs10802190
rs10923122
rs10924102
rs10924103
rs10924108
rs1109190
rs12025416
rs12031061
rs12044773
rs12044852i
rs1414275
rs17035862
rs17036001
rs17576615
rs35275493
rs35768283
rs3850814
rs4143029
rs4839073
rs55842195
rs6677309
rs7542681
rs758518
rs766429
rs871493
rs956184
rs9651076

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