MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs2760524

Polymorphism:

rs2760524

Gene:

RGS1 (1R20; BL34; IER1; IR20)

Protein:

regulator of G-protein signaling 1 (B-cell activation protein BL34; early response protein 1R20; immediate-early response 1, B-cell specific; regulator of G-protein signalling 1)

Chromosome:

1 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		A-Allele (frequency)	G-Allele (frequency)	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian	8	MS CTR	0.15 0.17	0.85 0.83	184 (0.023) 222 (0.029)	2061 (0.255) 2176 (0.280)	5840 (0.722) 5376 (0.692)
Other/Mixed	1	MS CTR	0.06 0.07	0.94 0.93	1 (0.005) 1 (0.005)	21 (0.107) 27 (0.137)	175 (0.888) 169 (0.858)
Total	9	MS CTR	0.15 0.17	0.85 0.83	185 (0.022) 223 (0.028)	2082 (0.251) 2203 (0.276)	6015 (0.726) 5545 (0.696)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs2760524

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs2816316

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