MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs5498

Polymorphism:

rs5498 (K469E)

Gene:

ICAM1 (BB2; CD54; P3.58)

View on ALSGene View on AlzGene View on PDGene View on SZGene

Protein:

intercellular adhesion molecule 1 (cell surface glycoprotein P3.58; human rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor)

Chromosome:

19 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		G-Allele (frequency)	A-Allele (frequency)	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian	5	MS CTR	0.43 0.47	0.57 0.53	171 (0.217) 240 (0.227)	333 (0.423) 511 (0.484)	284 (0.360) 305 (0.289)
Other/Mixed	1	MS CTR	0.48 0.53	0.53 0.47	37 (0.236) 39 (0.250)	75 (0.478) 86 (0.551)	45 (0.287) 31 (0.199)
Total	6	MS CTR	0.44 0.48	0.56 0.52	208 (0.220) 279 (0.230)	408 (0.432) 597 (0.493)	329 (0.348) 336 (0.277)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs5498 (K469E)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

ICAM1_2bpSTR
rs5491 (K56M)

Print this page

Email this page

MSDF RSS

Text size

Share & Bookmark

MSGene Recent Updates

MSGene Top Results