MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs2737191

Polymorphism:

rs2737191

Gene:

TLR4 (ARMD10; CD284; TOLL; hToll) View on AlzGene

Protein:

toll-like receptor 4(homolog of Drosophila toll)

Chromosome:

9 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		G-Allele (frequency)	A-Allele (frequency)	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian	1	MS CTR	0.27 0.24	0.73 0.76	27 (0.075) 31 (0.066)	141 (0.390) 160 (0.343)	194 (0.536) 276 (0.591)
Total	1	MS CTR	0.27 0.24	0.73 0.76	27 (0.075) 31 (0.066)	141 (0.390) 160 (0.343)	194 (0.536) 276 (0.591)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs2737191

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs10818073
rs11536869
rs12377632
rs1554973
rs1927907
rs1927911
rs2770146
rs4986791 (T399I)
rs5030717
rs7873784

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