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MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs4728142
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 Polymorphism: rs4728142
 Gene: IRF5 (SLEB10)
 Protein: interferon regulatory factor 5
 Chromosome: 7   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  A-Allele
(frequency)
G-Allele
(frequency)
A/A
(frequency)
A/G
(frequency)
G/G
(frequency)
 Caucasian 5 MS
CTR
0.49
0.45
0.51
0.55
763 (0.239)
709 (0.205)
1590 (0.499)
1713 (0.495)
835 (0.262)
1040 (0.300)
Total 5 MS
CTR
0.49
0.45
0.51
0.55
763 (0.239)
709 (0.205)
1590 (0.499)
1713 (0.495)
835 (0.262)
1040 (0.300)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs4728142

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

IRF5_indel (-/CGGGG)
rs10954213
rs11770589
rs12539741
rs2004640
rs2280714
rs3757385
rs729302

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MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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