MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs6897932

Polymorphism:

rs6897932

Gene:

IL7R (ILRA; IL7R; IL-7R-alpha; CDW127; IL7RA; CD127)

Protein:

interleukin 7 receptor

Chromosome:

5 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		T-Allele (frequency)	C-Allele (frequency)	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian	24	MS CTR	0.24 0.27	0.76 0.73	1038 (0.059) 1528 (0.076)	6349 (0.363) 8004 (0.396)	10099 (0.578) 10681 (0.528)
Other/Mixed	2	MS CTR	0.23 0.17	0.77 0.83	14 (0.047) 11 (0.037)	110 (0.370) 79 (0.267)	173 (0.582) 206 (0.696)
Total	26	MS CTR	0.24 0.27	0.76 0.73	1052 (0.059) 1539 (0.075)	6459 (0.363) 8083 (0.394)	10272 (0.578) 10887 (0.531)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs6897932

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

IL7R_541329/54148 (Leelab)
rs10058453
rs10461959
rs11567685 (-504T/C)
rs11567698
rs11567701
rs11567705
rs11567751
rs11567762
rs13169780
rs13188960
rs1389832
rs1494554
rs1494558
rs1494571
rs2303137
rs3777090
rs3822733
rs6870944
rs6871748
rs6897932i
rs7711202
rs7718919
rs7737000
rs969128

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