MSGene

MSGene - Gene overview of all published MS-association studies for LST1

Gene:

LST1 (DAAP-90L16.2; B144; D6S49E; LST-1; MGC119006; MGC119007)

View on SZGene

Protein:

leukocyte specific transcript 1 (leucocyte specific transcript 1; leukocyte-specific transcript 1 protein; lymphocyte antigen 117)

Chromosome:

6 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 1 December 2010

1. Case-Control Studies (by ethnic group)
				MS Cases				Normal Controls
Study	Population	Source	# Polys	# Subjects (% women)	DX	Onset Age (range)	Age (range)	# Subjects (% women)	Age (range)	Result
Caucasian
Kirk, 1997	UK (Northern Ireland)	CL	1 (detail)	189 (-)	U	-	-	206 (-)	-	Positive
McDonnell, 1999a	Ireland	CL	1 (detail)	276 (65%)	P	32.8 (-)	-	216 (-)	-	Negative

Contact us if you are an author of an association study regarding this gene and do not find your study in this table or find errors in the representation of your study details.

Source:  Source of case population -> “CL” (clinic-based), “PO” (population-based), or “CO” (community-based).
# Polys:  Number of polymorphisms tested per gene and per sample.
Onset Age and Age:  Mean or median age at onset or examination, respectively.
DX:  Criteria used to determine MS diagnosis -> "P" (Poser criteria, 1983), "MD1" (McDonald criteria, 2001), "MD2" (revised McDonald criteria, 2005), "MD1&2" (McDonald criteria, 2001 and 2005), "O/M" (other/mixed), "U" (Unknown).
Result:  Overall conclusion reached by authors of the original publication (“positive” usually indicates significant (P<0.05) association in at least one of the performed analyses, and “negative” indicates no evidence for significant association, while “trend” indicates results in between).
(-) :  Either no data provided or in case of overlap, data included in original study.

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