MSGene

MSGene - Polymorphism Details

Study:

Teutsch, 2004

Gene:

CD86 (B7-2; B70; CD28LG2; LAB72; MGC34413)

Protein:

CD86 molecule (B-lymphocyte activation antigen B7-2; B7-2 antigen; CD28 antigen ligand 2; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CTLA-4 counter-receptor B7.2)

Chromosome:

3 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Total number of polymorphisms investigated by this study: 2

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	C-Allele	A/A (frequency)	A/C (frequency)	C/C (frequency)
Caucasian
rs5852289 (-359delAAG)	Australia	MS CTR	0.42 0.42	0.58 0.58	20 (0.192) 23 (0.198)	48 (0.462) 51 (0.440)	36 (0.346) 42 (0.362)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs1129055	Australia	MS CTR	0.28 0.28	0.72 0.72	6 (0.056) 8 (0.069)	49 (0.454) 49 (0.422)	53 (0.491) 59 (0.509)