MSGene

MSGene - Polymorphism Details

Study:

Hoppenbrouwers, 2009

Gene:

CD58 (RP5-1086K13.2; FLJ23181; FLJ43722; LFA-3; LFA3)

Protein:

CD58 molecule (CD58 antigen, (lymphocyte function-associated antigen 3); surface glycoprotein LFA-3)

Chromosome:

1 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011 ;

***Note that content for MSGene is still being curated and that most currently displayed pages (including this page) contain preliminary summaries and are still incomplete.***

Total number of polymorphisms investigated by this study: 1

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	C-Allele	A/A (frequency)	A/C (frequency)	C/C (frequency)
Caucasian
rs12044852	Netherlands (outbred)	MS CTR	0.09 0.13	0.91 0.87	4 (0.008) 7 (0.016)	80 (0.163) 96 (0.226)	406 (0.829) 322 (0.758)
rs12044852	Overlaps with Aulchenko, 2008	MS CTR	0.12 0.11	0.88 0.89	1 (0.022) 2 (0.010)	9 (0.196) 38 (0.196)	36 (0.783) 154 (0.794)

*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Family-Based Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	C-Allele	A/A (frequency)	A/C (frequency)	C/C (frequency)
Caucasian
rs12044852	Canada	MS CTR	- -	- -	0 (-) 0 (-)	0 (-) 0 (-)	0 (-) 0 (-)

(-) : Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

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