MSGene

MSGene - Polymorphism Details

Study:

Mann, 2002

Gene:

PNMT (MGC34570; PENT; PNMTase)

View on AlzGene

Protein:

phenylethanolamine N-methyltransferase (noradrenaline N-methyltransferase; phenylethanolamine N-methylase)

Chromosome:

17 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 7 April 2010

Total number of polymorphisms investigated by this study: 2

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	A-Allele	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian
rs3764351 (-387G/A)	USA	MS CTR	0.45 0.40	0.55 0.60	34 (0.315) 149 (0.193)	29 (0.269) 328 (0.424)	45 (0.417) 297 (0.384)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	A-Allele	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian
rs876493 (-182G/A)	USA	MS CTR	0.33 0.42	0.67 0.58	11 (0.102) 152 (0.196)	50 (0.463) 343 (0.443)	47 (0.435) 279 (0.360)