MSGene

MSGene - Polymorphism Details

Study:

Aggelakis, 2009

Gene:

IL1RN (DIRA; ICIL-1RA; IL-1ra3; IL1F3; IL1RA; IRAP; MGC10430; MVCD4) View on AlzGene View on PDGene View on SZGene

Protein:

interleukin 1 receptor antagonist(IL1RN (IL1F3); OTTHUMP00000203730; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); type II interleukin-1 receptor antagonist)

Chromosome:

2 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		other-Allele	1-Allele	other/other (frequency)	other/1 (frequency)	1/1 (frequency)
Caucasian
*rs22346631 (86bpVNTR)**	Greece	MS CTR	0.25 0.26	0.75 0.74	27 (0.077) 29 (0.077)	121 (0.345) 135 (0.360)	203 (0.578) 211 (0.563)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		2-Allele	other-Allele	2/2 (frequency)	2/other (frequency)	other/other (frequency)
Caucasian
*rs22346632 (86bpVNTR)**	Greece	MS CTR	0.24 0.24	0.76 0.76	22 (0.063) 21 (0.056)	121 (0.345) 138 (0.368)	208 (0.593) 216 (0.576)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		3-Allele	other-Allele	3/3 (frequency)	3/other (frequency)	other/other (frequency)
Caucasian
*rs22346633 (86bpVNTR)**	Greece	MS CTR	0.01 0.01	0.99 0.99	0 (0.000) 0 (0.000)	9 (0.026) 11 (0.029)	342 (0.974) 364 (0.971)

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