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MSGene - Polymorphism Details
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 Study: Mann, 2002
 Gene: IL1RN (DIRA; ICIL-1RA; IL-1ra3; IL1F3; IL1RA; IRAP; MGC10430; MVCD4)   View on AlzGene   View on PDGene   View on SZGene
 Protein: interleukin 1 receptor antagonist(IL1RN (IL1F3); OTTHUMP00000203730; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); type II interleukin-1 receptor antagonist)
 Chromosome: 2   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   other-Allele 1-Allele other/other
(frequency)
other/1
(frequency)
1/1
(frequency)
 Caucasian
rs2234663*1 (86bpVNTR) UK MS
CTR
0.27
0.21
0.73
0.79
39 (0.088)
12 (0.076)
165 (0.373)
43 (0.274)
238 (0.538)
102 (0.650)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   2-Allele other-Allele 2/2
(frequency)
2/other
(frequency)
other/other
(frequency)
 Caucasian
rs2234663*2 (86bpVNTR) UK MS
CTR
0.25
0.18
0.75
0.82
34 (0.077)
8 (0.051)
154 (0.348)
40 (0.255)
254 (0.575)
109 (0.694)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   3-Allele other-Allele 3/3
(frequency)
3/other
(frequency)
other/other
(frequency)
 Caucasian
rs2234663*3 (86bpVNTR) UK MS
CTR
0.02
0.04
0.98
0.96
0 (0.000)
1 (0.006)
21 (0.048)
9 (0.057)
421 (0.952)
147 (0.936)
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MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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