MSGene

MSGene - Polymorphism Details

Study:

Hooper-van Veen, 2003

Gene:

IL1RN (DIRA; ICIL-1RA; IL-1ra3; IL1F3; IL1RA; IRAP; MGC10430; MVCD4) View on AlzGene View on PDGene View on SZGene

Protein:

interleukin 1 receptor antagonist(IL1RN (IL1F3); OTTHUMP00000203730; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); type II interleukin-1 receptor antagonist)

Chromosome:

2 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		other-Allele	1-Allele	other/other (frequency)	other/1 (frequency)	1/1 (frequency)
Caucasian
*rs22346631 (86bpVNTR)**	Netherlands	MS CTR	0.30 0.25	0.70 0.75	48 (0.110) 12 (0.074)	169 (0.388) 57 (0.350)	219 (0.502) 94 (0.577)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		2-Allele	other-Allele	2/2 (frequency)	2/other (frequency)	other/other (frequency)
Caucasian
*rs22346632 (86bpVNTR)**	Netherlands	MS CTR	0.27 0.23	0.73 0.77	33 (0.076) 12 (0.074)	166 (0.381) 50 (0.307)	237 (0.544) 101 (0.620)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		3-Allele	other-Allele	3/3 (frequency)	3/other (frequency)	other/other (frequency)
Caucasian
*rs22346633 (86bpVNTR)**	Netherlands	MS CTR	0.03 0.02	0.97 0.98	0 (0.000) 0 (0.000)	28 (0.064) 7 (0.043)	408 (0.936) 156 (0.957)

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