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MSGene - Polymorphism Details
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 Study: Zuvich, 2010
 Gene: BCL2  (Bcl-2)  Entrez Gene    View on AlzGene   View on PDGene
 Protein: B-cell CLL/lymphoma 2  (OTTHUMP00000163680; apoptosis regulator Bcl-2)  ProteinLink
 Chromosome: 18   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 4

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs8083921 USA, UK (I) MS
CTR		 0.27
0.31		 0.73
0.69		 129 (0.096)
142 (0.103)		 466 (0.348)
561 (0.407)		 746 (0.556)
675 (0.490)
rs8083921 USA, UK (II) MS
CTR		 0.27
0.28		 0.73
0.72		 170 (0.083)
167 (0.083)		 758 (0.368)
777 (0.387)		 1129 (0.549)
1063 (0.530)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   C-Allele T-Allele C/C
(frequency)		 C/T
(frequency)		 T/T
(frequency)
 Caucasian
rs8088739 USA, UK (I) MS
CTR		 0.28
0.24		 0.72
0.76		 99 (0.074)
89 (0.065)		 555 (0.414)
494 (0.358)		 688 (0.513)
796 (0.577)
rs8088739 USA, UK (II) MS
CTR		 0.26
0.25		 0.74
0.75		 152 (0.072)
131 (0.064)		 804 (0.381)
753 (0.370)		 1155 (0.547)
1152 (0.566)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs8092360 USA, UK (I) MS
CTR		 0.24
0.20		 0.76
0.80		 74 (0.055)
59 (0.043)		 486 (0.362)
424 (0.307)		 783 (0.583)
896 (0.650)
rs8092360 USA, UK (II) MS
CTR		 0.22
0.21		 0.78
0.79		 105 (0.050)
98 (0.048)		 713 (0.339)
647 (0.318)		 1287 (0.611)
1291 (0.634)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)		 Population   T-Allele C-Allele T/T
(frequency)		 T/C
(frequency)		 C/C
(frequency)
 Caucasian
rs9947451 USA, UK (I) MS
CTR		 0.28
0.24		 0.72
0.76		 105 (0.079)
79 (0.057)		 545 (0.409)
511 (0.371)		 682 (0.512)
789 (0.572)
rs9947451 USA, UK (II) MS
CTR		 0.26
0.26		 0.74
0.74		 132 (0.063)
136 (0.067)		 825 (0.391)
779 (0.382)		 1153 (0.546)
1123 (0.551)
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MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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