MSGene

MSGene - Polymorphism Details

Study:

Oeckinger, 2009

Gene:

CCL8 (HC14; MCP-2; MCP2; SCYA10; SCYA8) View on AlzGene

Protein:

chemokine (C-C motif) ligand 8(monocyte chemoattractant protein 2; monocyte chemotactic protein 2; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2))

Chromosome:

17 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs3138035	Sweden (II)	MS CTR	0.38 0.37	0.62 0.63	145 (0.155) 83 (0.127)	428 (0.457) 324 (0.495)	363 (0.388) 247 (0.378)
rs3138035	Denmark	MS CTR	0.37 0.38	0.63 0.62	60 (0.121) 71 (0.135)	243 (0.489) 255 (0.485)	194 (0.390) 200 (0.380)
rs3138035	Sweden (I)	MS CTR	0.39 0.40	0.61 0.60	152 (0.156) 160 (0.152)	456 (0.468) 513 (0.488)	367 (0.376) 379 (0.360)
rs3138035	Norway	MS CTR	0.39 0.36	0.61 0.64	83 (0.157) 76 (0.148)	246 (0.465) 223 (0.433)	200 (0.378) 216 (0.419)
rs3138035	Finland	MS CTR	0.40 0.40	0.60 0.60	127 (0.159) 157 (0.149)	380 (0.477) 522 (0.495)	290 (0.364) 376 (0.356)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		G-Allele	A-Allele	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian
rs3138036	Sweden (I)	MS CTR	0.17 0.16	0.83 0.84	16 (0.016) 22 (0.020)	298 (0.303) 313 (0.278)	671 (0.681) 789 (0.702)
rs3138036	Norway	MS CTR	0.16 0.15	0.84 0.85	16 (0.030) 13 (0.025)	141 (0.267) 126 (0.245)	372 (0.703) 376 (0.730)
rs3138036	Denmark	MS CTR	0.14 0.15	0.86 0.85	12 (0.024) 11 (0.021)	119 (0.239) 133 (0.251)	367 (0.737) 385 (0.728)
rs3138036	Finland	MS CTR	0.16 0.16	0.84 0.84	15 (0.019) 22 (0.021)	223 (0.277) 284 (0.269)	568 (0.705) 748 (0.710)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		C-Allele	A-Allele	C/C (frequency)	C/A (frequency)	A/A (frequency)
Caucasian
rs3138038	Norway	MS CTR	0.16 0.15	0.84 0.85	16 (0.030) 13 (0.025)	144 (0.268) 127 (0.246)	378 (0.703) 376 (0.729)
rs3138038	Denmark	MS CTR	0.15 0.15	0.85 0.85	13 (0.026) 11 (0.021)	125 (0.247) 135 (0.252)	369 (0.728) 390 (0.728)
rs3138038	Sweden (I)	MS CTR	0.18 0.16	0.82 0.84	16 (0.016) 20 (0.017)	322 (0.321) 318 (0.278)	665 (0.663) 807 (0.705)
rs3138038	Finland	MS CTR	0.16 0.16	0.84 0.84	15 (0.019) 22 (0.021)	223 (0.277) 284 (0.269)	568 (0.705) 748 (0.710)

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