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MSGene - Polymorphism Details
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 Study: Oeckinger, 2009
 Gene: CCL2 (GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; MGC9434; SCYA2; SMC-CF)   View on AlzGene   View on PDGene   View on SZGene
 Protein: chemokine (C-C motif) ligand 2(monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; monocyte secretory protein JE; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2)
 Chromosome: 17   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 4

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs13900 Sweden (I) MS
CTR
0.28
0.29
0.72
0.71
71 (0.072)
98 (0.087)
402 (0.409)
469 (0.415)
511 (0.519)
562 (0.498)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele G-Allele C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian
rs2857656 Sweden (I) MS
CTR
0.28
0.30
0.72
0.70
70 (0.072)
100 (0.087)
405 (0.414)
481 (0.419)
504 (0.515)
566 (0.493)
rs2857656 Sweden (II) MS
CTR
0.28
0.27
0.72
0.73
69 (0.083)
43 (0.074)
321 (0.387)
231 (0.398)
440 (0.530)
307 (0.528)
rs2857656 Norway MS
CTR
0.30
0.27
0.70
0.73
41 (0.081)
38 (0.078)
219 (0.430)
189 (0.386)
249 (0.489)
263 (0.537)
rs2857656 Denmark MS
CTR
0.29
0.25
0.71
0.75
36 (0.085)
32 (0.068)
176 (0.417)
175 (0.371)
210 (0.498)
265 (0.561)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele C-Allele G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian
rs2857657 Sweden (I) MS
CTR
0.18
0.17
0.82
0.83
35 (0.036)
33 (0.028)
286 (0.294)
332 (0.286)
651 (0.670)
797 (0.686)
rs2857657 Sweden (II) MS
CTR
0.18
0.17
0.82
0.83
28 (0.030)
19 (0.029)
270 (0.290)
188 (0.288)
633 (0.680)
445 (0.683)
rs2857657 Norway MS
CTR
0.19
0.18
0.81
0.82
17 (0.033)
16 (0.032)
164 (0.320)
151 (0.302)
332 (0.647)
333 (0.666)
rs2857657 Denmark MS
CTR
0.17
0.17
0.83
0.83
23 (0.049)
19 (0.037)
109 (0.234)
136 (0.264)
333 (0.716)
360 (0.699)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele T-Allele C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
 Caucasian
rs4586 Sweden (I) MS
CTR
0.36
0.38
0.64
0.62
114 (0.117)
160 (0.145)
469 (0.480)
511 (0.462)
394 (0.403)
436 (0.394)
rs4586 Sweden (II) MS
CTR
0.36
0.37
0.64
0.63
133 (0.143)
93 (0.144)
394 (0.425)
296 (0.457)
401 (0.432)
259 (0.400)
rs4586 Norway MS
CTR
0.35
0.37
0.65
0.63
66 (0.125)
72 (0.141)
235 (0.445)
229 (0.450)
227 (0.430)
208 (0.409)
rs4586 Denmark MS
CTR
0.38
0.34
0.62
0.66
69 (0.141)
66 (0.126)
235 (0.481)
227 (0.434)
185 (0.378)
230 (0.440)
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Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
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MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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