MSGene

MSGene - Polymorphism Details

Study:

Oeckinger, 2009

Gene:

CCL1 (I-309; P500; SCYA1; SISe; TCA3)

Protein:

chemokine (C-C motif) ligand 1(T lymphocyte-secreted protein I-309; inflammatory cytokine I-309; small inducible cytokine A1; small inducible cytokine A1 (I-309, homologous to mouse Tca-3))

Chromosome:

17 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs159279	Sweden (I)	MS CTR	0.07 0.07	0.93 0.93	2 (0.002) 4 (0.004)	134 (0.136) 162 (0.143)	851 (0.862) 969 (0.854)
rs159279	Denmark	MS CTR	0.06 0.08	0.94 0.92	0 (0.000) 2 (0.004)	62 (0.123) 81 (0.152)	444 (0.877) 449 (0.844)
rs159279	Norway	MS CTR	0.08 0.07	0.92 0.93	3 (0.006) 3 (0.006)	78 (0.147) 68 (0.133)	448 (0.847) 440 (0.861)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs3136682	Sweden (II)	MS CTR	0.02 0.02	0.98 0.98	0 (0.000) 0 (0.000)	40 (0.043) 31 (0.047)	896 (0.957) 623 (0.953)
rs3136682	Sweden (I)	MS CTR	0.02 0.02	0.98 0.98	0 (0.000) 0 (0.000)	30 (0.031) 49 (0.043)	935 (0.969) 1102 (0.957)
rs3136682	Norway	MS CTR	0.02 0.02	0.98 0.98	0 (0.000) 0 (0.000)	18 (0.034) 17 (0.033)	507 (0.966) 499 (0.967)
rs3136682	Denmark	MS CTR	0.01 0.03	0.99 0.97	0 (0.000) 0 (0.000)	14 (0.028) 29 (0.055)	480 (0.972) 501 (0.945)
rs3136682	Finland	MS CTR	0.01 0.02	0.99 0.98	0 (0.000) 0 (0.000)	20 (0.025) 48 (0.045)	780 (0.975) 1008 (0.955)

Case-Control Studies (by ethnic group)
					Genotypes
Polymorphism ID# (Link to NCBI)	Population		A-Allele	G-Allele	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian
rs3138032	Sweden (I)	MS CTR	0.09 0.08	0.91 0.92	7 (0.007) 8 (0.007)	160 (0.160) 176 (0.152)	835 (0.833) 975 (0.841)
rs3138032	Denmark	MS CTR	0.08 0.09	0.92 0.91	1 (0.002) 5 (0.009)	82 (0.162) 83 (0.155)	422 (0.836) 448 (0.836)
rs3138032	Finland	MS CTR	0.06 0.05	0.94 0.95	2 (0.002) 1 (0.001)	94 (0.117) 69 (0.099)	709 (0.881) 626 (0.899)
rs3138032	Norway	MS CTR	0.09 0.08	0.91 0.92	4 (0.008) 5 (0.010)	87 (0.163) 70 (0.135)	442 (0.829) 442 (0.855)

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