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MSGene - Polymorphism Details
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 Study: Sawcer, 2003
 Gene: NOD2 (ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1)   View on PDGene
 Protein: nucleotide-binding oligomerization domain containing 2(NLR family, CARD domain containing 2; NOD-like receptor C2; caspase recruitment domain family, member 15; caspase recruitment domain protein 15; inflammatory bowel disease protein 1; nucleotide-binding oligomerization domain 2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2)
 Chromosome: 16   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs2066844 (R675W) Overlaps with WTCCC, 2007 MS
CTR
0.05
0.06
0.95
0.94
1 (0.002)
1 (0.003)
58 (0.092)
40 (0.117)
572 (0.906)
302 (0.880)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   C-Allele G-Allele C/C
(frequency)
C/G
(frequency)
G/G
(frequency)
 Caucasian
rs2066845 (G1881R) Overlaps with WTCCC, 2007 MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   ins-Allele del-Allele ins/ins
(frequency)
ins/del
(frequency)
del/del
(frequency)
 Caucasian
rs2066847 (2936-indel) Overlaps with WTCCC, 2007 MS
CTR
0.02
0.01
0.98
0.99
0 (0.000)
0 (0.000)
29 (0.046)
8 (0.023)
602 (0.954)
335 (0.977)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.
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MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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