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MSGene - Polymorphism Details
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 Study: IMSGC, 2009
 Gene: ERBB3 (ErbB-3; HER3; LCCS2; MDA-BF-1; MGC88033; c-erbB-3; c-erbB3; erbB3-S; p180-ErbB3; p45-sErbB3; p85-sErbB3)   View on SZGene
 Protein: v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)(erbB-3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3)
 Chromosome: 12   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 1

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs2292239 Belgium MS
CTR
0.32
0.33
0.68
0.67
42 (0.106)
51 (0.111)
174 (0.437)
206 (0.447)
182 (0.457)
204 (0.443)
rs2292239 Norway MS
CTR
0.33
0.33
0.67
0.67
72 (0.112)
109 (0.107)
287 (0.446)
450 (0.440)
285 (0.443)
464 (0.454)
rs2292239 UK MS
CTR
0.34
0.36
0.66
0.64
171 (0.113)
897 (0.127)
675 (0.446)
3245 (0.458)
668 (0.441)
2936 (0.415)
rs2292239 USA MS
CTR
0.34
0.34
0.66
0.66
152 (0.116)
64 (0.114)
588 (0.449)
252 (0.449)
571 (0.436)
245 (0.437)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele G-Allele T/T
(frequency)
T/G
(frequency)
G/G
(frequency)
 Caucasian
rs2292239 Australia MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs2292239 Belgium MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs2292239 UK MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs2292239 USA MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
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Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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