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MSGene - Polymorphism Details
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 Study: Cavanillas, 2010
 Gene: IL2RA  (RP11-536K7.1; CD25; IDDM10; IL2R; TCGFR)  Entrez Gene    View on PDGene
 Protein: interleukin 2 receptor, alpha  (Interleukin-2 receptor; interleukin 2 receptor, alpha chain)  ProteinLink
 Chromosome: 10   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 3

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele C-Allele A/A
(frequency)
A/C
(frequency)
C/C
(frequency)
 Caucasian
rs41295061 Overlaps with Alcina, 2009 MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs41295061 Spain (I) MS
CTR
0.04
0.06
0.96
0.94
1 (0.002)
2 (0.004)
35 (0.084)
66 (0.121)
381 (0.914)
479 (0.876)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   G-Allele A-Allele G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian
rs2104286 Spain (I) MS
CTR
0.15
0.21
0.85
0.79
8 (0.019)
25 (0.046)
108 (0.258)
183 (0.336)
303 (0.723)
337 (0.618)
rs2104286 Overlaps with Alcina, 2009 MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)


Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   A-Allele T-Allele A/A
(frequency)
A/T
(frequency)
T/T
(frequency)
 Caucasian
rs11594656 Overlaps with Alcina, 2009 MS
CTR
0.37
0.33
0.63
0.67
105 (0.136)
82 (0.111)
366 (0.475)
320 (0.435)
300 (0.389)
334 (0.454)
rs11594656 Spain (I) MS
CTR
0.34
0.31
0.66
0.69
56 (0.135)
48 (0.088)
172 (0.415)
244 (0.449)
186 (0.449)
251 (0.462)
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MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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