MSGene

MSGene - Polymorphism Details

Study:

Reindl, 2003

Gene:

TLR4 (ARMD10; CD284; TOLL; hToll) View on AlzGene

Protein:

toll-like receptor 4(homolog of Drosophila toll)

Chromosome:

9 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Total number of polymorphisms investigated by this study: 2

Case-Control Studies (by ethnic group)
					Genotypes*
Polymorphism ID# (Link to NCBI)	Population		G-Allele	A-Allele	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian
rs4986790 (D299G)	Austria	MS CTR	0.06 0.07	0.94 0.93	0 (0.000) 0 (0.000)	23 (0.121) 13 (0.137)	167 (0.879) 82 (0.863)

*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
					Genotypes*
Polymorphism ID# (Link to NCBI)	Population		T-Allele	C-Allele	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian
rs4986791 (T399I)	Austria	MS CTR	0.06 0.07	0.94 0.93	0 (0.000) 0 (0.000)	22 (0.116) 13 (0.137)	168 (0.884) 82 (0.863)

*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

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