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MSGene - Polymorphism Details
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 Study: IMSGC, 2008
 Gene: IL7R  (ILRA; IL7R; IL-7R-alpha; CDW127; IL7RA; CD127)  Entrez Gene
 Protein: interleukin 7 receptor   ProteinLink
 Chromosome: 5   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Meta-Analysis     Gene Overview
Total number of polymorphisms investigated by this study: 2

Case-Control Studies (by ethnic group)
  Genotypes*
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs6897932 Overlaps with ANZgene, 2009 (Australia) MS
CTR
0.24
0.23
0.76
0.77
28 (0.059)
23 (0.054)
174 (0.369)
151 (0.356)
270 (0.572)
250 (0.590)
rs6897932 Belgium MS
CTR
0.22
0.27
0.78
0.73
20 (0.049)
34 (0.074)
139 (0.343)
183 (0.396)
246 (0.607)
245 (0.530)
rs6897932 Denmark MS
CTR
0.23
0.29
0.77
0.71
27 (0.053)
45 (0.083)
179 (0.354)
222 (0.410)
299 (0.592)
274 (0.506)
rs6897932 Germany MS
CTR
0.23
0.25
0.77
0.75
11 (0.053)
39 (0.064)
73 (0.354)
229 (0.379)
122 (0.592)
337 (0.557)
rs6897932 Italy MS
CTR
0.20
0.23
0.80
0.77
33 (0.038)
41 (0.053)
272 (0.315)
273 (0.352)
558 (0.647)
461 (0.595)
rs6897932 Overlaps with Sanna, 2010 MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs6897932 UK (Northern Ireland) MS
CTR
0.27
0.26
0.73
0.74
49 (0.072)
37 (0.070)
267 (0.391)
207 (0.389)
367 (0.537)
288 (0.541)
rs6897932 Norway MS
CTR
0.26
0.29
0.74
0.71
50 (0.068)
88 (0.086)
283 (0.383)
426 (0.415)
405 (0.549)
513 (0.500)
rs6897932 Spain MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs6897932 UK MS
CTR
0.24
0.28
0.76
0.72
133 (0.057)
225 (0.076)
845 (0.364)
1183 (0.400)
1345 (0.579)
1552 (0.524)
rs6897932 USA MS
CTR
0.22
0.26
0.78
0.74
67 (0.048)
162 (0.066)
477 (0.342)
939 (0.381)
851 (0.610)
1365 (0.554)
rs6897932 Overlaps with Kallio, 2009 (Finland) MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs6897932 Overlaps with Lundmark, 2007 (Sweden) MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
*Genotypes have been calculated from allele frequencies assuming Hardy-Weinberg equilibrium.

Case-Control Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs6897932i Overlaps with Hoppenbrouwers, 2009 (Netherlands) MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).

Family-Based Studies (by ethnic group)
  Genotypes
Polymorphism ID#
(Link to NCBI)
Population   T-Allele C-Allele T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian
rs6897932 Finland MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs6897932 France MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs6897932 Italy (Sardinia) MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs6897932 Overlaps with Ban, 2009 (USA) MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs6897932 Overlaps with Gregory, 2007 (Belgium) MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
rs6897932 Overlaps with Gregory, 2007 (UK) MS
CTR
-
-
-
-
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
0 (-)
(-) :  Either no data provided, or data otherwise not eligible for inclusion (see methods for details).
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MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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