Multiple Sclerosis Discovery Forum
  News and Future Directions
  Papers
  Forums
  Professional Resources
  Research Resources
MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs231775
Back Search Methods Disclaimer Credits
 Polymorphism: rs231775 (49A/G)
 Gene: CTLA4  (CD; CD152; CELIAC3; CTLA-4; GSE; IDDM12)  Entrez Gene    View on SZGene
 Protein: cytotoxic T-lymphocyte-associated protein 4  (celiac disease 3; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated serine esterase-4; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4)  ProteinLink
 Chromosome: 2   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
A-Allele
(frequency)
G/G
(frequency)
G/A
(frequency)
A/A
(frequency)
 Caucasian 20 MS
CTR
0.39
0.39
0.61
0.61
697 (0.153)
630 (0.155)
2154 (0.472)
1941 (0.478)
1710 (0.375)
1492 (0.367)
 Asian 2 MS
CTR
0.58
0.65
0.42
0.36
56 (0.320)
106 (0.438)
92 (0.526)
100 (0.413)
27 (0.154)
36 (0.149)
 Other/Mixed 4 MS
CTR
0.34
0.31
0.66
0.69
67 (0.122)
52 (0.107)
237 (0.433)
200 (0.410)
243 (0.444)
236 (0.484)
Total 26 MS
CTR
0.39
0.40
0.61
0.60
820 (0.155)
788 (0.164)
2483 (0.470)
2241 (0.468)
1980 (0.375)
1764 (0.368)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs231775 (49A/G)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

CTLA4_2bpSTR-3'UTR
CTLA4_6230A/G
rs10197010 (7482)
rs10932025 (12131)
rs11571297 (12310C/T)
rs11571302 (10242G/T)
rs11571315 (-1765)
rs11571316 (-1577A/G)
rs11571317 (-658C/T)
rs11571319 (6249)
rs231723 (7092)
rs231725 (7982)
rs237155
rs4553808 (-1661)
rs733618 (-1722)
rs7565213 (10717A/G)
SARA-1 (STR)
SARA-43 (STR)

Print this page
Email this page
MSDF RSS

Text size
Share & Bookmark
MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
Copyright © 2024 Biomedical Research Forum LLC Disclaimer Copyright