MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs724710

Polymorphism:

rs724710

Gene:

BCL2L11 (BAM; BIM; BIM-alpha6; BIM-beta6; BIM-beta7; BOD; BimEL; BimL)

View on SZGene

Protein:

BCL2-like 11 (apoptosis facilitator) (BCL2-like 11; OTTHUMP00000197013; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist)

Chromosome:

2 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		T-Allele (frequency)	C-Allele (frequency)	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian	1	MS CTR	0.31 0.33	0.69 0.67	61 (0.094) 75 (0.115)	284 (0.436) 284 (0.437)	306 (0.470) 291 (0.448)
Total	1	MS CTR	0.31 0.33	0.69 0.67	61 (0.094) 75 (0.115)	284 (0.436) 284 (0.437)	306 (0.470) 291 (0.448)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs724710

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1980045
rs2018707
rs686952

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