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MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs1061622
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 Polymorphism: rs1061622 (676T/G)
 Gene: TNFRSF1B  (CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR)  Entrez Gene    View on ALSGene   View on AlzGene   View on SZGene
 Protein: tumor necrosis factor receptor superfamily, member 1B  (p75 TNF receptor; soluble TNFR1B variant 1; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; tumor necrosis factor receptor 2)  ProteinLink
 Chromosome: 1   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
T-Allele
(frequency)
G/G
(frequency)
G/T
(frequency)
T/T
(frequency)
 Caucasian 2 MS
CTR
0.26
0.24
0.74
0.76
63 (0.064)
20 (0.044)
377 (0.383)
179 (0.397)
544 (0.553)
252 (0.559)
Total 2 MS
CTR
0.26
0.24
0.74
0.76
63 (0.064)
20 (0.044)
377 (0.383)
179 (0.397)
544 (0.553)
252 (0.559)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs1061622 (676T/G)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1061624 (1663G/A)
rs1061631
rs3397 (1690T/C)
rs5030792 (1668T/G)
rs5746026 (783G/A)

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MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
ALSGene
AlzGene
MSGene
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An up-to-date collection of all published genetic association studies.
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