MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs1061622

Polymorphism:

rs1061622 (676T/G)

Gene:

TNFRSF1B (CD120b; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80; p75; p75TNFR)

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Protein:

tumor necrosis factor receptor superfamily, member 1B (p75 TNF receptor; soluble TNFR1B variant 1; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; tumor necrosis factor receptor 2)

Chromosome:

1 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		G-Allele (frequency)	T-Allele (frequency)	G/G (frequency)	G/T (frequency)	T/T (frequency)
Caucasian	2	MS CTR	0.26 0.24	0.74 0.76	63 (0.064) 20 (0.044)	377 (0.383) 179 (0.397)	544 (0.553) 252 (0.559)
Total	2	MS CTR	0.26 0.24	0.74 0.76	63 (0.064) 20 (0.044)	377 (0.383) 179 (0.397)	544 (0.553) 252 (0.559)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs1061622 (676T/G)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1061624 (1663G/A)
rs1061631
rs3397 (1690T/C)
rs5030792 (1668T/G)
rs5746026 (783G/A)

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