MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs2857657

Polymorphism:

rs2857657

Gene:

CCL2 (GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; MGC9434; SCYA2; SMC-CF) View on AlzGene View on PDGene View on SZGene

Protein:

chemokine (C-C motif) ligand 2(monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; monocyte secretory protein JE; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2)

Chromosome:

17 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		G-Allele (frequency)	C-Allele (frequency)	G/G (frequency)	G/C (frequency)	C/C (frequency)
Caucasian	4	MS CTR	0.18 0.17	0.82 0.83	103 (0.036) 87 (0.031)	829 (0.288) 807 (0.285)	1949 (0.677) 1935 (0.684)
Total	4	MS CTR	0.18 0.17	0.82 0.83	103 (0.036) 87 (0.031)	829 (0.288) 807 (0.285)	1949 (0.677) 1935 (0.684)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs2857657

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1024610 (-2138A/T)
rs1024611 (-2581A/G)
rs13900
rs3760396

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