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MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs2857657
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 Polymorphism: rs2857657
 Gene: CCL2 (GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; MGC9434; SCYA2; SMC-CF)   View on AlzGene   View on PDGene   View on SZGene
 Protein: chemokine (C-C motif) ligand 2(monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; monocyte secretory protein JE; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2)
 Chromosome: 17   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  G-Allele
(frequency)
C-Allele
(frequency)
G/G
(frequency)
G/C
(frequency)
C/C
(frequency)
 Caucasian 4 MS
CTR
0.18
0.17
0.82
0.83
103 (0.036)
87 (0.031)
829 (0.288)
807 (0.285)
1949 (0.677)
1935 (0.684)
Total 4 MS
CTR
0.18
0.17
0.82
0.83
103 (0.036)
87 (0.031)
829 (0.288)
807 (0.285)
1949 (0.677)
1935 (0.684)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs2857657

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1024610 (-2138A/T)
rs1024611 (-2581A/G)
rs13900
rs3760396

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MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
ALSGene
AlzGene
MSGene
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An up-to-date collection of all published genetic association studies.
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