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MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs3918244
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 Polymorphism: rs3918244 (-1562C/T)
 Gene: MMP9 (CLG4B; GELB; MMP-9)   View on ALSGene   View on AlzGene   View on SZGene
 Protein: matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)(macrophage gelatinase; matrix metalloproteinase 9; matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); type V collagenase)
 Chromosome: 20   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 25 November 2011
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  T-Allele
(frequency)
C-Allele
(frequency)
T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian 5 MS
CTR
0.16
0.15
0.84
0.85
30 (0.027)
19 (0.021)
295 (0.266)
232 (0.251)
782 (0.706)
672 (0.728)
 Other/Mixed 1 MS
CTR
0.15
0.10
0.85
0.90
6 (0.038)
3 (0.016)
35 (0.222)
32 (0.168)
117 (0.741)
156 (0.817)
Total 6 MS
CTR
0.16
0.14
0.84
0.86
36 (0.028)
22 (0.020)
330 (0.261)
264 (0.237)
899 (0.711)
828 (0.743)

Meta-Analysis Methods      * New * Cumulative Meta-analysis
2) Forest plot for polymorphism  rs3918244 (-1562C/T)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs17576 (R279Q)
rs72370883 (2bpSTR)

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MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
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