MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs763361

Polymorphism:

rs763361 (S307G)

Gene:

CD226 (DNAM-1; DNAM1; PTA1; TLiSA1)

Protein:

CD226 molecule (CD226 antigen; DNAX accessory molecule-1; T lineage-specific activation antigen 1 antigen; adhesion glycoprotein; platelet and T cell activation antigen 1)

Chromosome:

18 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		T-Allele (frequency)	C-Allele (frequency)	T/T (frequency)	T/C (frequency)	C/C (frequency)
Caucasian	8	MS CTR	0.49 0.46	0.51 0.54	2396 (0.243) 3295 (0.215)	4891 (0.495) 7546 (0.493)	2592 (0.262) 4450 (0.291)
Other/Mixed	1	MS CTR	0.53 0.46	0.47 0.54	56 (0.284) 41 (0.208)	98 (0.497) 98 (0.497)	43 (0.218) 58 (0.294)
Total	9	MS CTR	0.49 0.46	0.51 0.54	2452 (0.243) 3336 (0.215)	4989 (0.495) 7644 (0.494)	2635 (0.262) 4508 (0.291)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs763361 (S307G)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs1009847
rs1124980
rs11661553
rs12604328
rs17208329
rs17842596
rs1788114
rs1788234
rs4891781

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