Multiple Sclerosis Discovery Forum
  News and Future Directions
  Papers
  Forums
  Professional Resources
  Research Resources
MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs7412
Back Search Methods Disclaimer Credits
 Polymorphism: rs7412 (e2)
 Gene: APOE  (AD2; LDLCQ5; LPG; MGC1571)  Entrez Gene    View on ALSGene   View on AlzGene   View on PDGene   View on SZGene
 Protein: apolipoprotein E  (apolipoprotein E3)  ProteinLink
 Chromosome: 19   (View: 1  2  3  4  5  6  7  8  9  10  11  12  13  14  15  16  17  18  19  20  21  22  X  Y  MT)
 Status: Updated 24 July 2010
Gene Overview
 Polymorphism:
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
      Alleles Genotypes
  # Case-Control
Samples
  T-Allele
(frequency)
C-Allele
(frequency)
T/T
(frequency)
T/C
(frequency)
C/C
(frequency)
 Caucasian 15 MS
CTR
0.08
0.05
0.92
0.95
22 (0.008)
17 (0.004)
404 (0.142)
398 (0.099)
2415 (0.850)
3590 (0.896)
 Asian 1 MS
CTR
0.04
0.04
0.96
0.96
0 (0.000)
0 (0.000)
11 (0.081)
10 (0.075)
124 (0.919)
124 (0.925)
 Other/Mixed 1 MS
CTR
0.01
0.06
0.99
0.94
0 (0.000)
2 (0.019)
1 (0.026)
8 (0.075)
38 (0.974)
96 (0.906)
Total 17 MS
CTR
0.08
0.05
0.92
0.95
22 (0.007)
19 (0.004)
416 (0.138)
416 (0.098)
2577 (0.855)
3810 (0.898)

Meta-Analysis Methods
2) Forest plot for polymorphism  rs7412 (e2)

Please also see disclaimer for more information on these meta-analyses.


Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs7412 (e2)

Print this page
Email this page
MSDF RSS

Text size
Share & Bookmark
MSGene Recent Updates
MSGene Top Results
Top Results Details
1. HLA-DRB1
2. IL2RA
3. IL7R
4. TAGAP
5. CLEC16A
6. EVI5
7. GWA_16q24.1
8. GWA_5p13.1
9. TTC34
10. AHI1   
[see more]
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
ALSGene
AlzGene
MSGene
PDGene
SZGene
An up-to-date collection of all published genetic association studies.
Copyright © 2021 Biomedical Research Forum LLC Disclaimer Copyright