MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs1805011

Polymorphism:

rs1805011 (E375A)

Gene:

IL4R (CD124; IL4RA) View on SZGene

Protein:

interleukin 4 receptor(OTTHUMP00000122506; interleukin 4 receptor alpha chain; interleukin-4 receptor alpha chain)

Chromosome:

16 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		G-Allele (frequency)	T-Allele (frequency)	G/G (frequency)	G/T (frequency)	T/T (frequency)
Caucasian	4	MS CTR	0.11 0.11	0.89 0.89	43 (0.017) 34 (0.012)	481 (0.187) 554 (0.197)	2050 (0.796) 2223 (0.791)
Total	4	MS CTR	0.11 0.11	0.89 0.89	43 (0.017) 34 (0.012)	481 (0.187) 554 (0.197)	2050 (0.796) 2223 (0.791)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs1805011 (E375A)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

IL4R_ (-3223))
IL4R_1902A/G
rs1029489
rs1110470
rs12102586
rs16976728
rs1805010 (I50V)
rs1805012 (C406R)
rs1805013 (S411L)
rs1805014 (S761P)
rs2234895 (N142N)
rs2234897
rs2234898 (L389L)
rs2234900
rs2239349
rs2301807
rs3024530
rs3024560
rs3024585
rs3024613
rs3024634
rs3024668
rs3024698
rs3116578
rs4787423
rs6498011
rs8057585
rs8832

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