MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs2228570

Polymorphism:

rs2228570 (rs10735810_FokI)

Gene:

VDR (NR1I1) View on ALSGene View on AlzGene View on PDGene View on SZGene

Protein:

vitamin D (1,25- dihydroxyvitamin D3) receptor(vitamin D (1,25-dihydroxyvitamin D3) receptor)

Chromosome:

12 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		A-Allele (frequency)	G-Allele (frequency)	A/A (frequency)	A/G (frequency)	G/G (frequency)
Caucasian	5	MS CTR	0.37 0.39	0.63 0.61	132 (0.139) 153 (0.161)	445 (0.467) 441 (0.464)	375 (0.394) 357 (0.375)
Total	5	MS CTR	0.37 0.39	0.63 0.61	132 (0.139) 153 (0.161)	445 (0.467) 441 (0.464)	375 (0.394) 357 (0.375)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs2228570 (rs10735810_FokI)

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

rs11568820
rs11608702 (C_3290614_10)
rs1989969 (C_12060044_1)
rs2254210
rs4516035
rs7139166
rs7976091 (C_2880811_10)
rs98784

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