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MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs1800693
Polymorphism:
rs1800693
Gene:
TNFRSF1A
(CD120a; FPF; MGC19588; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR55; TNFR60; p55; p55-R; p60)
View on ALSGene
View on AlzGene
View on PDGene
Protein:
tumor necrosis factor receptor superfamily, member 1A
(tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1; tumor necrosis factor receptor type 1; tumor necrosis factor-alpha receptor)
Chromosome:
12
(View:
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
X
Y
MT
)
Status:
Updated 25 November 2011
Polymorphism:
rs1800693 (significant)
rs1860545 (significant)
rs4149584 (significant)
1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
Alleles
Genotypes
# Case-Control
Samples
C-Allele
(frequency)
T-Allele
(frequency)
C/C
(frequency)
C/T
(frequency)
T/T
(frequency)
Caucasian
2
MS
CTR
0.50
0.48
0.50
0.52
242 (0.248)
221 (0.231)
487 (0.499)
471 (0.493)
246 (0.252)
263 (0.275)
Total
2
MS
CTR
0.50
0.48
0.50
0.52
242 (0.248)
221 (0.231)
487 (0.499)
471 (0.493)
246 (0.252)
263 (0.275)
Meta-Analysis Methods
* New *
Cumulative Meta-analysis
2) Forest plot for polymorphism
rs1800693
Please also
see disclaimer
for more information on these meta-analyses.
Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see
methods
for details):
rs767455
TNFRSF1A_2bpSTR
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MSGene Recent Updates
STAT3
MSGene Top Results
Top Results Details
1.
HLA-DRB1
2.
IL2RA
3.
IL7R
4.
TAGAP
5.
CLEC16A
6.
EVI5
7.
GWA_16q24.1
8.
GWA_5p13.1
9.
TTC34
10.
AHI1
[see more]
[close]
11.
GWA_3q24
12.
CD226
13.
CD5
14.
IL12B
15.
PLEK
16.
IL22RA2
17.
NCOA5
18.
STAT3
19.
GWA_2p21
20.
DKKL1
21.
CYP24A1
22.
TNFRSF1A
23.
TNFSF14
24.
CD86
25.
CD58
26.
GWA_3q12.3
27.
SH2B3
28.
SP140
29.
GPR65
30.
CYP27B1
31.
CD40
32.
MAPK1
33.
ZFP36L1
34.
AGAP2
35.
RPS6KB1
36.
SOX8
37.
MPV17L2
38.
PTPRK
39.
ZMIZ1
40.
PVR
41.
HHEX
42.
C1orf106
43.
PKIA
44.
BACH2
45.
MMEL1
46.
SLC30A7
47.
BATF
48.
KIF21B
49.
SAE1
50.
DLEU1
51.
MYC
52.
SYK
53.
RGS14
54.
DDAH1
55.
MERTK
56.
ZNF767
57.
CLECL1
58.
MANBA
59.
TYK2
60.
ZBTB46
61.
CDC37
62.
NDFIP1
63.
MAP3K14
64.
RGS1
65.
TMEM39A
66.
MALT1
67.
CARD11
68.
MAF
69.
IRF5
MSGene Stats
Studies: 789
Genes: 809
Polymorphisms: 2907
Meta-analyses: 324
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An up-to-date collection of all published genetic association studies.
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