MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs2870957

Polymorphism:

rs2870957

Gene:

IFNG (IFG; IFI) View on AlzGene View on PDGene View on SZGene

Protein:

interferon, gamma

Chromosome:

12 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		G-Allele (frequency)	T-Allele (frequency)	G/G (frequency)	G/T (frequency)	T/T (frequency)
Caucasian	3	MS CTR	0.22 0.23	0.79 0.77	52 (0.062) 36 (0.043)	258 (0.306) 311 (0.373)	533 (0.632) 487 (0.584)
Total	3	MS CTR	0.22 0.23	0.79 0.77	52 (0.062) 36 (0.043)	258 (0.306) 311 (0.373)	533 (0.632) 487 (0.584)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs2870957

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

D12S313
IFNG_2bpSTR (intron1)
IFNG_3'UTR-5644T/A
IFNG_874A/T
rs10878766
rs1118866
rs1861494
rs2069705
rs2216165
rs2430561
rs3181034
rs7135373
rs7954499

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