MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs2104286

Polymorphism:

rs2104286

Gene:

IL2RA (RP11-536K7.1; CD25; IDDM10; IL2R; TCGFR)

View on PDGene

Protein:

interleukin 2 receptor, alpha (Interleukin-2 receptor; interleukin 2 receptor, alpha chain)

Chromosome:

10 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		G-Allele (frequency)	A-Allele (frequency)	G/G (frequency)	G/A (frequency)	A/A (frequency)
Caucasian	17	MS CTR	0.22 0.25	0.78 0.75	772 (0.049) 1211 (0.066)	5282 (0.337) 6839 (0.375)	9607 (0.613) 10204 (0.559)
Other/Mixed	2	MS CTR	0.22 0.24	0.78 0.76	15 (0.038) 36 (0.059)	143 (0.359) 223 (0.365)	240 (0.603) 352 (0.576)
Total	19	MS CTR	0.22 0.25	0.78 0.75	787 (0.049) 1247 (0.066)	5425 (0.338) 7062 (0.374)	9847 (0.613) 10556 (0.560)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs2104286

Please also see disclaimer for more information on these meta-analyses.

Meta-analyses have not been performed on the following polymorphisms since they lack published genotype data in at least four independent case-control samples, or the published genotype data was otherwise not eligible for inclusion (see methods for details):

IL2RA_unknownSNPs
rs10795791
rs10905713
rs11256369
rs11594656
rs12722605
rs1570538
rs2104286i
rs3134883
rs35285258
rs41295061
rs4147359
rs7076103
rs7090512
rs7090530
rs791589

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