MSGene

MSGene - Meta-Analysis of All Published MS Association Studies (Case-Control Only) rs1801274

Polymorphism:

rs1801274 (R131H)

Gene:

FCGR2A (RP11-5K23.6; CD32; CD32A; CDw32; FCG2; FCGR2; FCGR2A1; FcGR; IGFR2; MGC23887; MGC30032)

Protein:

Fc fragment of IgG, low affinity IIa, receptor (CD32) (Fc fragment of IgG, low affinity IIa, receptor; Immunoglobulin G Fc receptor II)

Chromosome:

1 (View: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y MT)

Status:

Updated 25 November 2011

Polymorphism:

1) Summary of Allele and Genotype Distribution of all Published Association Studies (by Ethnic Group)
			Alleles		Genotypes
	# Case-Control Samples		R-Allele (frequency)	H-Allele (frequency)	R/R (frequency)	R/H (frequency)	H/H (frequency)
Caucasian	3	MS CTR	0.48 0.49	0.52 0.51	173 (0.259) 190 (0.239)	297 (0.445) 395 (0.497)	198 (0.296) 209 (0.263)
Other/Mixed	1	MS CTR	0.38 0.40	0.62 0.60	22 (0.147) 16 (0.118)	70 (0.467) 77 (0.566)	58 (0.387) 43 (0.316)
Total	4	MS CTR	0.46 0.48	0.54 0.53	195 (0.238) 206 (0.222)	367 (0.449) 472 (0.508)	256 (0.313) 252 (0.271)

Meta-Analysis Methods * New * Cumulative Meta-analysis

2) Forest plot for polymorphism rs1801274 (R131H)

Please also see disclaimer for more information on these meta-analyses.

Email this page

MSDF RSS

Text size

MSGene Recent Updates

MSGene Top Results